BACKGROUND. The aim of this study was to evaluate the cost-effectiveness, f
rom a societal perspective, of the Finnish nationwide breast carcinoma scre
ening program.
METHODS. The effects were measured in life-years saved from 1987 to 2020, u
sing data from the nationwide program to the end of 1992. A total of 90,000
women ages 50-59 were invited for screening during the years 1987-89. The
total number of participants screened was 76,000. The screening interval wa
s 24 months, with follow-up to the end of 1992. From the beginning of 1993,
the estimation model used parameters based on published studies and nation
al cancer statistics. Data on health care and non-health care costs and tim
e costs were obtained from internal accounts of screening units, published
studies, national statistics, health market sources, and a questionnaire co
mpleted by a sample of 1400 screening attendees. The discount rate, the ann
ual rate of time preference over future costs and life-years saved, was 3%.
The main outcome measure was the cost per life-year saved.
RESULTS. The estimated number of life-years of life saved was 578, of which
8% occurred 1987-1992. The estimated life-years saved per 1000 screenings
was 3.2. The total costs were $11 million in U.S. dollars, i.e., $14.3 mill
ion per 100,000 participants.
CONCLUSIONS. The cost of breast carcinoma mammographic screening per life-y
ear saved was $18,955 in the base case, ranging from $15,502 to $40,308 acc
ording to the different models used in analysis. Cancer 1999;86:638-46. (C)
1999 American Cancer Society.