A macromolecular Gd(III) complex as pH-responsive relaxometric probe for MRI applications

Citation
S. Aime et al., A macromolecular Gd(III) complex as pH-responsive relaxometric probe for MRI applications, CHEM COMMUN, (16), 1999, pp. 1577-1578
Citations number
13
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
16
Year of publication
1999
Pages
1577 - 1578
Database
ISI
SICI code
1359-7345(19990821):16<1577:AMGCAP>2.0.ZU;2-Q
Abstract
The ability of the paramagnetic macromolecular complex (GdDO3ASQ)(30)-Orn(1 14) to enhance the water proton relaxation rate has been found to be a func tion of pH; this behaviour is related to the structural changes occurring i n the polypeptide upon protonation of the side-chain NH2 groups.