Unexpected formation of beta-lactams and penem isosteres from mesoionics: sequential ring-opening-rearrangement of [3+2] cycloadducts

Authors
Avalos, M Babiano, R Cintas, P Hursthouse, MB Jimenez, JL Light, ME Lopez, I Palacios, JC
Citation
M. Avalos et al., Unexpected formation of beta-lactams and penem isosteres from mesoionics: sequential ring-opening-rearrangement of [3+2] cycloadducts, CHEM COMMUN, (16), 1999, pp. 1589-1590
Citations number
13
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
16
Year of publication
1999
Pages
1589 - 1590
Database
ISI
SICI code
1359-7345(19990821):16<1589:UFOBAP>2.0.ZU;2-H
Abstract
A novel and simple method has been developed to obtain penem analogs with b iologically interesting functionalities, which combines aromatic aldehydes with thioisomunchnones, a readily available class of mesoionic heterocycles .