Citation
C. Perollier et al., High-yield synthesis of a chiroporphyrin by hydrogen bond-directed cyclisation, CHEM COMMUN, (16), 1999, pp. 1597-1598
Citations number
18
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345
→ ACNP
Issue
16
Year of publication
1999
Pages
1597 - 1598
Database
ISI
SICI code
1359-7345(19990821):16<1597:HSOACB>2.0.ZU;2-X
Abstract
A new chiroporphyrin is prepared in 60% yield using complementary intramole
cular hydrogen-bonding interactions between N-acylurea substituents to dire
ct the cyclisation of the tetrapyrrolic intermediate; similar hydrogen-bond
assistance by carboxylic acid functions is suggested for cyclisation of hy
droxymethylbilane to uroporphyrinogen I.