Importance of product desorption in enantioselective hydrogenation of (E)-alpha-phenylcinnamic acid with a cinchonidine-modified Pd/TiO2 catalyst: Effect of additives
Y. Nitta, Importance of product desorption in enantioselective hydrogenation of (E)-alpha-phenylcinnamic acid with a cinchonidine-modified Pd/TiO2 catalyst: Effect of additives, CHEM LETT, (7), 1999, pp. 635-636
Addition of amines, especially benzylamine, to the reaction mixture of (E)-
alpha-phenylcinnamic acid with a cinchonidine-modified palladium catalyst r
esulted in much enhanced activities and fairly increased enantioselectiviti
es. The preferential acceleration of the selective reaction is attributable
to the effective desorption, assisted by the added base, of the hydrogenat
ed molecules from the modified sites.