Microbial 7-OH epimerisation of bile acids

Authors
Dean, M Fantin, G Fogagnolo, M Medici, A Pedrini, P Poli, S
Citation
M. Dean et al., Microbial 7-OH epimerisation of bile acids, CHEM LETT, (7), 1999, pp. 693-694
Citations number
9
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022 → ACNP
Issue
7
Year of publication
1999
Pages
693 - 694
Database
ISI
SICI code
0366-7022(199907):7<693:M7EOBA>2.0.ZU;2-1
Abstract
The microbial 7-OH epimerisation of cholic and chenodeoxycholic acids with Xanthomonas maltophilia CBS 827.97 to ursocholic and ursodeoxycholic acids with scarsity of oxygen is described. With normal pressure of oxygen the 7- ketocholic and the 7-ketochenodeoxycholic acids are obtained. No biotransfo rmation is achieved in anaerobic conditions.