Supramolecular principles: conformational changes in the hydrogen-bonded host lattice of N,N '-ditosyl-p-phenylenediamine support the inclusion of rigid guest molecules

Crystals of thirteen novel inclusion compounds with a host lattice of N,N'- ditosyl-p-phenylenediamine were investigated. The conformational flexibilit y and the acidic hydrogens of the sulfonamide links enable the incorporatio n of a variety of guest molecules within the cavities of the host matrix. T he crystalline host-guest aggregates can be subdivided into clathrates with weak interactions between host and guest and lattice inclusion compounds w ith energetically favorable host...guest hydrogen bonds;the clathrates migh t be further classified according to their sulfonamide...sulfonamide hydrog en bond motifs as well as to the N,N'-ditosyl-p-phenylenediamine conformati ons within the host lattices containing different cavities for guest molecu le insertion.