The role of twin studies in the genetics of skin diseases

Authors
Bataille, V
Citation
V. Bataille, The role of twin studies in the genetics of skin diseases, CLIN EXP D, 24(4), 1999, pp. 286-290
Citations number
36
Categorie Soggetti
Dermatology
Journal title
CLINICAL AND EXPERIMENTAL DERMATOLOGY
ISSN journal
03076938 → ACNP
Volume
24
Issue
4
Year of publication
1999
Pages
286 - 290
Database
ISI
SICI code
0307-6938(199907)24:4<286:TROTSI>2.0.ZU;2-1
Abstract
With advances in molecular biology and statistical techniques; gene discove ry is moving at a fast pace, Most skin diseases have a complex mode of inhe ritance and the twin design is the ideal model to dissect the genetic archi tecture. Use of the twin pairings in a variety of ways for associations and linkage studies can enhance gene discovery. This review covers the advanta ges and limitations of the twin method.