Plant-based production of xenogenic proteins

Citation
Ee. Hood et Jm. Jilka, Plant-based production of xenogenic proteins, CURR OPIN B, 10(4), 1999, pp. 382-386
Citations number
27
Categorie Soggetti
Microbiology
Journal title
CURRENT OPINION IN BIOTECHNOLOGY
ISSN journal
09581669 → ACNP
Volume
10
Issue
4
Year of publication
1999
Pages
382 - 386
Database
ISI
SICI code
0958-1669(199908)10:4<382:PPOXP>2.0.ZU;2-C
Abstract
Foreign protein production in transgenic plants has been successful, from t he generation of transgenic plant lines to the marketing of purified protei ns. Antigenic proteins from disease organisms, monoclonal antibodies raised against antigens of disease organisms, and proteins with industrial proces s applications have been produced and tested. For vaccines, clinical trials in humans and feeding trials in animals are in progress to demonstrate the ir efficacy. For industrial proteins, high expression and downstream proces sing efficiency are key concerns, with application and test market trials i n progress.