T cell responses to bacterial infection

Many exciting advances in our understanding of T cell mediated immunity to bacterial infection have occurred in the past several years. T cell respons es have been more fully characterized, due in part to the development of MH C class I tetramers. The importance of cytokines and various effector molec ules in defense against infection has come to light. Finally, intracellular bacteria are being exploited to deliver antigens and DNA in an effort to i nduce immunity to pathogens.