Designing polymers that mimic biomolecules

Citation
K. Kirshenbaum et al., Designing polymers that mimic biomolecules, CURR OP STR, 9(4), 1999, pp. 530-535
Citations number
63
Categorie Soggetti
Biochemistry & Biophysics
Journal title
CURRENT OPINION IN STRUCTURAL BIOLOGY
ISSN journal
0959440X → ACNP
Volume
9
Issue
4
Year of publication
1999
Pages
530 - 535
Database
ISI
SICI code
0959-440X(199908)9:4<530:DPTMB>2.0.ZU;2-7
Abstract
A new field is emerging. Chemists are beginning to synthesize polymers with properties that are similar to those of proteins and RNA. Recent studies h ave identified oligomer backbones that form stable secondary structures. It is now possible to assemble specific sequences of diverse monomer sets int o chain lengths that are nearly sufficient for tertiary structure formation . Such molecules will teach us how natural biopolymers fold; they will also enable us to design synthetic heteropolymers with novel structures and des irable functions.