A. Baykal et al., Effect of intraperitoneal and extraperitoneal insertion of mesh on bacterial translocation: Does it make a difference?, EURO J SURG, 165(4), 1999, pp. 378-382
Objective: To asses the effect of insertion of mesh, with or without contac
t with the peritoneum, on the induction of bacterial translocation.
Design: Open experimental study.
Setting: Surgical research laboratory, Turkey.
Subjects: 158 Swiss albino mice.
Interventions: A defect in the abdominal wall was created. In the control g
roup, the defect was closed primarily. In the extraperitoneal group, polypr
opylene mesh was sutured over the abdominal wall after primary closure of t
he peritoneum and in the intraperitoneal group, polypropylene mesh was sutu
red to close the created defect so that it was in contact with the intestin
es.
Main outcome measures: Bacterial translocation at 4, 24 and 48 hours.
Results: Insertion of mesh in contact with the peritoneum led to increased
bacterial translocation to mesenteric lymph nodes at 4 (p = 0.02) and 48 (p
= 0.03) hours compared with insertion without contact.
Conclusion: Contact between a foreign body and the peritoneum is required t
o induce bacterial translocation.