Pm. Simone et Gc. Baylis, SELECTIVE ATTENTION IN A REACHING TASK - EFFECT OF NORMAL AGING AND ALZHEIMERS-DISEASE, Journal of experimental psychology. Human perception and performance, 23(3), 1997, pp. 595-608
This study examined the ability of young adults, older adults, and old
er adults suffering from Alzheimer's disease (AD) to perform a selecti
ve reaching task. Normal aging did not increase interference caused by
distracters. In contrast, patients with AD showed massively increased
effects of distracter interference. AD patients showed a high probabi
lity of making responses to distracter items. The proportion of these
incorrect responses was related to the inability to use inhibitory pro
cesses, which increased with the severity of AD. Responses to distract
ers occurred despite the fact that patients could discriminate targets
and distracters and knew that their responses to distracters were in
error. These data suggest that AD patients are impaired in their abili
ty to inhibit incorrect responses.