Preparation of 4-(2-aminoethyl)-3,3-dimethyl-2-piperidone derivatives by intramolecular rearrangement of alpha,alpha-dimethyl-4-piperidineacetyl chloride
Jl. Binet et al., Preparation of 4-(2-aminoethyl)-3,3-dimethyl-2-piperidone derivatives by intramolecular rearrangement of alpha,alpha-dimethyl-4-piperidineacetyl chloride, HETEROCYCLE, 51(7), 1999, pp. 1573
Reaction of hindered amines with alpha,alpha-dimethyl-4-piperidineacetyl ch
loride provided 4-(2-aminoethyl)-3,3-dimethyl-2-piperidone derivatives by i
ntramolecular rearrangement of the acid chloride.