G. Heinisch et al., Pyridazines, 90. On the synthesis of novel 1,2-diazine containing tricyclic systems: Preparation of tetra-azaphenazines, HETEROCYCLE, 51(7), 1999, pp. 1625
Reaction of 6-chloro-N-(3,6-dichloropyridazin-4-yl)-3-(4-methoxybenzyl-amin
o)-N-propylpyridazine-4-carboxamide (1) under strong basic conditions or wi
th a weak base at high temperature was found to result in a ring contractio
n to give two isomeric tetraazaphenazines. A tentative mechanism is propose
d.