Severe ovarian hyperstimulation syndrome following salvage of empty follicle syndrome

We report a case of severe ovarian hyperstimulation syndrome (OHSS) followi ng a rescue of empty follicle syndrome (EFS). This suggests that the risk o f developing OHSS remains unaltered even in the presence of EFS. The case s upports the possibility of obtaining oocytes that fertilize and cleave norm ally after a second dose of human chorionic gonadotrophin (HCG) and a repea t oocyte retrieval. It supports the suggestion that the follicles are not n ecessarily empty in EFS. It demonstrates further that OHSS cannot be preven ted by aspiration of follicular fluid and patients with large numbers of fo llicles and EFS must be warned of this potential complication.