The stability of Runge-Kutta methods for systems of delay differential equa
tions (DDEs) with multiple delays is considered. The stability regions of e
xplicit and implicit Runge-Kutta methods are discussed when they are applie
d to asymptotically stable linear DDEs with multiple delays. A simple estim
ate on the stability regions of explicit Runge-Kutta methods is presented.
It is shown that the stable step-size for numerical integration of DDEs wit
h multiple delays can be easily selected by means of the estimate.