Analysis of B-cell epitopes of the Ro/SS-A autoantigen

Authors
Wahren-Herlenius, M Muller, S Isenberg, D
Citation
M. Wahren-herlenius et al., Analysis of B-cell epitopes of the Ro/SS-A autoantigen, IMMUNOL TOD, 20(5), 1999, pp. 234-240
Citations number
57
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGY TODAY
ISSN journal
01675699 → ACNP
Volume
20
Issue
5
Year of publication
1999
Pages
234 - 240
Database
ISI
SICI code
0167-5699(199905)20:5<234:AOBEOT>2.0.ZU;2-Y
Abstract
Autoantibodies to the Ro and La ribonucleoprotein antigens are found in sev eral rheumatoid diseases. The important epitopes have been studied using sy nthetic peptides and recombinant antigens to understand how they arise and their implication in disease. Here, we analyse the results of epitope mappi ng studies of Ro60 and Ro52 autoantigens and focus on the major findings to date.