The design of plantwide control systems has received increasing attention i
n the past few years. This paper deals with how one can systematically synt
hesize plantwide control architectures from steady-state process models usi
ng optimization. The optimization problem solved is a mixed-integer Linear
programming (MILP) problem which aims at minimizing valve movement to compe
nsate for a disturbance. Results are presented for its application to the T
ennessee Eastman test-bed process.