BMIPP compared with thallium redistribution

I-123 labeled methyl-branched fatty acid, BMIPP, has been used mainly in Eu rope and Japan for the evaluation of various cardiac diseases. BMIPP uptake abnormality is usually more prominent than perfusion, representing discord ant BMIPP uptake less than thallium. This finding is observed in various ca rdiac disease conditions such as acute myocardial infarction, stable and un stable angina, hypertrophic and dilated cardiomyopathies. Many BMIPP studie s combined stress thallium imaging in patients with coronary artery disease and hypertrophic cardiomyopathy demonstrated that such discordant BMIPP up take less than thallium is related to stress-induced ischemia as evidenced by reversible thallium defect after exercise. BMIPP imaging is able to dete ct metabolic alteration in the heart which is not available by perfusion im aging alone.