We examine a nonlocal interaction that results from expressing the QCD Hami
ltonian entirely in terms of gauge-invariant quark and gluon fields. The in
teraction couples one quark color-charge density to another, much as electr
ic charge densities are coupled to each other by the Coulomb interaction in
QED. In QCD, this nonlocal interaction also couples quark color-charge den
sities to gluonic color. We show how the leading part of the interaction be
tween quark color-charge densities vanishes when the participating quarks a
re in a color singlet configuration, and that, for singlet configurations,
the residual interaction weakens as the size of a packet of quarks shrinks.
Because of this effect, color-singlet packets of quarks should experience
final state interactions that increase in strength as these packets expand
in size. For the case of an SU(2) model of QCD based on the ansatz that the
gauge-invariant gauge field is a hedgehog configuration, we show how the i
nfinite series that represents the nonlocal interaction between quark color
-charge densities can be evaluated nonperturbatively, without expanding it
term-by-term. We discuss the implications of this model for QCD with SU(3)
color and a gauge-invariant gauge field determined by QCD dynamics.