CHLAMYDIA-TRACHOMATIS GROWTH STIMULATES INTERLEUKIN-8 PRODUCTION BY HUMAN MONOCYTIC U-937 CELLS

Authors
BIANCHI A DOSQUET C HENRY S COUDERC MC FERCHAL F SCIEUX C
Citation
A. Bianchi et al., CHLAMYDIA-TRACHOMATIS GROWTH STIMULATES INTERLEUKIN-8 PRODUCTION BY HUMAN MONOCYTIC U-937 CELLS, Infection and immunity, 65(6), 1997, pp. 2434-2436
Citations number
22
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
65
Issue
6
Year of publication
1997
Pages
2434 - 2436
Database
ISI
SICI code
0019-9567(1997)65:6<2434:CGSIPB>2.0.ZU;2-P
Abstract
Growth of Chlamydia trachomatis serotypes L2 and L3 in a human monocyt ic cell line, U-937, increased the rate of interleukin 8 (IL-8) releas e 100-fold, Heat-killed chlamydiae induced a 10-fold-lower level of pr oduction of IL-8. IL-8 mag play an important role in the inflammatory reaction to chlamydial infection.