AVIRULENCE OF LT2 STRAINS OF SALMONELLA-TYPHIMURIUM RESULTS FROM A DEFECTIVE RPOS GENE

Authors
SWORDS WE CANNON BM BENJAMIN WH
Citation
We. Swords et al., AVIRULENCE OF LT2 STRAINS OF SALMONELLA-TYPHIMURIUM RESULTS FROM A DEFECTIVE RPOS GENE, Infection and immunity, 65(6), 1997, pp. 2451-2453
Citations number
26
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
65
Issue
6
Year of publication
1997
Pages
2451 - 2453
Database
ISI
SICI code
0019-9567(1997)65:6<2451:AOLSOS>2.0.ZU;2-1
Abstract
In order to identify the genetic basis for the attenuation of Salmonel la typhimurium LT2 strains, experiments were performed to identify a g ene(s) which restores virulence to an avirulent LT2 strain. These and further experiments confirmed that an rpoS mutation is the sole determ inant of the attenuation of S. typhimurium LT2.