Background: This study reviews the results of an initial experience with mi
nimally invasive coronary bypass surgery using the Port-Access(TM) approach
in terms of early outcome and safety. Methods: Between October 1996 and Ju
ly 1997 49 Port-Access(TM) minimally invasive coronary artery bypass grafti
ng procedures were performed at our institution. The patients' mean age was
59.8 years (range 34 to 82 years). Sixteen patients received single vessel
and 37 patients received multivessel bypass grafts. Results: There were no
operative deaths and no perioperative myocardial infarctions, neurological
deficits, or conversions to sternotomy. Early complications included reope
ration due to bleeding in 4 patients, reoperation for a pulmonary embolus i
n 1 patient, and angioplasty for occlusion of a right coronary artery graft
in 2 patients. postoperative angiograms were obtained in 86% (42/49) of th
e patients and showed 100% patency for left internal mammary artery to left
anterior descending artery grafts and 96% patency for all grafts. Conclusi
ons: These results demonstrate that Port-Access(TM) coronary artery bypass
grafting using endovascular techniques for cardiopulmonary bypass and cardi
oplegic arrest can be performed safely with minimal morbidity and mortality
. This technique allows multivessel revascularization on a protected, arres
ted heart with excellent anastomotic precision and reproducible early graft
patency. Expanded use of Port-Access(TM) techniques is indicated in patien
ts with multivessel coronary artery disease and the technique should be con
sidered for patients with left anterior descending artery restenosis and pa
tients with complex left anterior descending artery lesions where angioplas
ty results are suboptimal.