Successful suppression of cutaneous cryptococcal infection in an immunocompromised patient with fluconazole

An immunosuppressed patient with pancytopenia developed cryptococcal cellul itis over his thighs, confirmed by histopathologic, serologic and cultural studies. Culture of the blood, CSF, sputum, and urine were negative for Cry ptococcus. A decision to put the patient on fluconazole alone was made. By the 53rd week, his serologic examination for cryptococcal antigen had becom e negative, He was likewise clinically cured of the infection and fluconazo le was discontinued.