Rotational atherectomy has long been regarded as contraindicated for stenot
ic lesions within the body of saphenous vein grafts. So far, reports of rot
ational atherectomy in vein grafts have been concerned with ostial and dist
al anastomotic lesions. We report the first two cases of the successful use
of the Rotablator for discrete lesions of mid-saphenous vein grafts. No co
mplications were encountered. One patient is doing well 6 months after the
procedure, and the other patient continues to do well more than 1 year late
r.