(R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides are orally active inhibitors of pyruvate dehydrogenase kinase

Aicher, TD Anderson, RC Bebernitz, GR Coppola, GM Jewell, CF Knorr, DC Liu, C Sperbeck, DM Brand, LJ Strohschein, RJ Gao, JP Vinluan, CC Shetty, SS Dragland, C Kaplan, EL DelGrande, D Islam, A Liu, XL Lozito, RJ Maniara, WM Walter, RE Mann, WR

Td. Aicher et al., (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides are orally active inhibitors of pyruvate dehydrogenase kinase, J MED CHEM, 42(15), 1999, pp. 2741-2746

52

Chemistry & Analysis

JOURNAL OF MEDICINAL CHEMISTRY

00222623 → ACNP

42

15

1999

2741 - 2746

ISI

0022-2623(19990729)42:15<2741:(AOAI>2.0.ZU;2-M