Olanzapine for psychosis in patients with Parkinson's disease with and without dementia

Authors
Aarsland, D Larsen, JP Lim, NG Tandberg, E
Citation
D. Aarsland et al., Olanzapine for psychosis in patients with Parkinson's disease with and without dementia, J NEUROP CL, 11(3), 1999, pp. 392-394
Citations number
12
Categorie Soggetti
Neurology
Journal title
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
ISSN journal
08950172 → ACNP
Volume
11
Issue
3
Year of publication
1999
Pages
392 - 394
Database
ISI
SICI code
0895-0172(199922)11:3<392:OFPIPW>2.0.ZU;2-K
Abstract
Twenty-one patients with Parkinson's disease and psychosis were included in an open-label 8-week trial of olanzapine. Eight subjects had dementia. Six subjects (29%) discontinued treatment prematurely because of drowsiness. D elusions and hallucinations improved significantly, and 80% were rated as m uch or very much improved. There was no worsening of parkinsonism or cognit ion.