Adociasalfates 1, 7, and 8: New bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp.

Authors
Kalaitzis, JA Leone, PD Harris, L Butler, MS Ngo, A Hooper, JNA Quinn, RJ
Citation
Ja. Kalaitzis et al., Adociasalfates 1, 7, and 8: New bioactive hexaprenoid hydroquinones from the marine sponge Adocia sp., J ORG CHEM, 64(15), 1999, pp. 5571-5574
Citations number
6
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
00223263 → ACNP
Volume
64
Issue
15
Year of publication
1999
Pages
5571 - 5574
Database
ISI
SICI code
0022-3263(19990723)64:15<5571:A17A8N>2.0.ZU;2-G
Abstract
Adociasulfate 1 (1), adociasulfate 7 (2), and adociasulfate 8 (3), which ar e inhibitors of proton pump activity in hen bone-derived membrane vesicles, were isolated from an extract of the sponge Adocia sp. (Chalinidae). Struc ture elucidation by 2D-NMR spectroscopy revealed that they are novel hexapr enoid hydroquinone sulfates.