Citation
Jf. Hartwig et al., Room-temperature palladium-catalyzed amination of aryl bromides and chlorides and extended scope of aromatic C-N bond formation with a commercial ligand, J ORG CHEM, 64(15), 1999, pp. 5575-5580
Citations number
64
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
00223263
→ ACNP
Volume
64
Issue
15
Year of publication
1999
Pages
5575 - 5580
Database
ISI
SICI code
0022-3263(19990723)64:15<5575:RPAOAB>2.0.ZU;2-N
Abstract
The reactions of aryl bromides with amines occurs at room temperature when
using Pd(0) and P(t-Bu)(3) in a 1:1 ratio, and the reactions of aryl chlori
des occur at room temperature or 70 degrees C. The arylation of indoles and
the new arylation of carbamates also occur when using P(t-Bu)(3) as ligand
.