Early reactive neutrophil changes in an infant with Kawasaki syndrome

An infant with Kawasaki syndrome presenting with fever, rash, and a high pe rcentage of neutrophils with toxic granulation is reported. The peripheral blood smears of the patient showed a high proportion of neutrophils with ma rked vacuoles and toxic granulations. The reactive changes in neutrophils c ould be helpful in the early detection of the disease, especially in infant s younger than 6 months of age who are at high risk for development of coro nary artery disease.