Monomers, polymers, copolymers, resins, and coated silicas containing benzylamine residues planned as artificial substrates of benzylamine oxidase

The new monomers 3-(3-methacryloxypropoxy)benzylamine and 4-(3-methacryloxy propoxy)benzylamine in the form of hydrochlorides have been synthesized and radically copolymerized under various conditions with comonomers of differ ent hydrophilicity, including N-acryloylmorpholine, N-acryloylpyrrolidine, N,N-dimethylacrylamide, and N-vinylbenzoylmorpholine, to obtain linear solu ble, granular crosslinked, and silica-based macromolecular systems designed for investigating the action mechanism of benzylamine oxidase. Some charac teristics of the prepared materials, including scanning electron microscopy photographs, are reported. (C) 1999 John Wiley & Sons, Inc.