Citation
Y. Sawaishi et al., Positron emission tomography in juvenile Alexander disease, J NEUR SCI, 165(2), 1999, pp. 116-120
Citations number
15
Categorie Soggetti
Neurosciences & Behavoir
Journal title
JOURNAL OF THE NEUROLOGICAL SCIENCES
ISSN journal
0022510X
→ ACNP
Volume
165
Issue
2
Year of publication
1999
Pages
116 - 120
Database
ISI
SICI code
0022-510X(19990601)165:2<116:PETIJA>2.0.ZU;2-W
Abstract
A 13-year-old boy with cervical kyphosis was diagnosed as having juvenile A
lexander disease because of the typical MRI findings, abnormally elevated a
lpha B-crystallin and heat shock protein 27 in the cerebrospinal fluid. Pos
itron emission tomography with F-18-fluoro-deoxyglucose demonstrated hypome
tabolism in the frontal white matter corresponding to the areas with leukod
ystrophy. However, the overlying gray matter preserved normal glucose metab
olism. (C) 1999 Elsevier Science B.V. All rights reserved.