Objective: The purpose of this study is to review indications, surgical pro
cedures, and outcomes in adults with repaired tetralogy of Fallot referred
for reoperation. Method: Sixty consecutive adults (age greater than or equa
l to 18 years) who underwent reoperation between 1975 and 1997 after previo
us repair of tetralogy of Fallot were reviewed. Mean age at corrective repa
ir was 13.3 +/- 9.6 years and at reoperation 33.3 +/- 9.6 years. Mean follo
w-up after reoperation is 5.0 +/- 4.9 years. Results: Long-term complicatio
ns of the right ventricular outflow tract (n = 45, 75%) were the most commo
n indications for reoperation: severe pulmonary regurgitation (n = 23, 38%)
and conduit failure (n = 13, 22%) were most frequent. Less common indicati
ons were ventricular septal patch leak (n = 6) and severe tricuspid regurgi
tation (n = 3). A history of sustained ventricular tachycardia was present
in 20 patients (33%) and supraventricular tachycardia occurred in 9 patient
s (15%). A bioprosthetic valve to reconstruct the right ventricular outflow
tract was used in 42 patients, Additional procedures (n = 115) to correct
other residual lesions were required in 46 patients (77%). There was no per
ioperative mortality. Actuarial 10-year survival is 92% +/- 6%. At most rec
ent follow-up, 93% of the patients are in New York Heart Association classi
fication I or II. Sustained ventricular tachycardia occurred in 4 patients
(7%) during follow-up. Conclusions: Long-term complications of the right ve
ntricular outflow tract were the main reason for reoperation. Mid-term surv
ival and functional improvement after reoperation are excellent.