Synthesis and stereochemical features of 2-oxo-3-cyano-1,2-thiaphosphorinanes

Authors
Odinets, IL Vinogradova, NM Artyushin, OI Petrovskii, PV Lyssenko, KA Antipin, MY Mastryukova, TA
Citation
Il. Odinets et al., Synthesis and stereochemical features of 2-oxo-3-cyano-1,2-thiaphosphorinanes, MENDELEEV C, (4), 1999, pp. 158-160
Citations number
8
Categorie Soggetti
Chemistry
Journal title
MENDELEEV COMMUNICATIONS
ISSN journal
09599436 → ACNP
Issue
4
Year of publication
1999
Pages
158 - 160
Database
ISI
SICI code
0959-9436(199907):4<158:SASFO2>2.0.ZU;2-J
Abstract
The intramolecular Pishchimuka rearrangement of 3-halopropyl-substituted th iophosphorylacetonitriles results in the corresponding 2-oxo-3-cyano-1,2-th iaphosphorinanes as a statistical mixture of two diastereomers, which trans forms to an individual diastereomer with time; in benzene solution, the lat ter turns again into an equilibrium mixture of diastereomers.