Effect of ultraviolet light irradiation and nitrosoguanidine on viability of 46 strains of Arthrinium and their antibiotic production

The ability of strains of the Arthrinium genus to inhibit microbial develop ment has been previously described. In the present work different periods o f mutagenic treatment using ultraviolet light, and of nitrosoguanidine trea tment, on strains of Arthrinium were investigated. With nitrosoguanidine tr eatment the survival rate ranged from 2.17 to 8.78%. Mutant strains were on ly obtained with a higher antibiotic production in comparison with the wild -strain, when the mutagenic agent was UV light.