An event-related potential examination of masked and unmasked repetition priming in Alzheimer's disease: Implications for theories of implicit memory

Fifteen patients diagnosed with Alzheimer's disease (AD) and 26 matched old er controls engaged in a lexical-decision task with a list of words and non words while event-related brain potentials (ERPs) were recorded. Two repeti tion conditions were embedded in the list: words repeated at relatively lon g lags or words repeated shortly after a brief masked presentation. Althoug h older controls displayed behavioral and ERP repetition priming for words repeated at long lags, consistent with previous studies, AD patients displa yed neither. in contrast, both controls and AD patients displayed an ERP re petition priming effect for words repeated shortly after a brief masked pre sentation. ERP priming effects for masked and unmasked repetition differed in older controls, and additionally, the ERP masked priming effect differed between controls and AD patients. Results are discussed in the context of studies that have examined memory performance in brain-damaged populations using an impaired-intact dichotomy.