Synthesis and biophysical studies of modified oligonucleotides containing acyclic amino alcohol nucleoside analogs

Citation
Ks. Ramasamy et V. Stoisavljevic, Synthesis and biophysical studies of modified oligonucleotides containing acyclic amino alcohol nucleoside analogs, NUCLEOS NUC, 18(8), 1999, pp. 1845-1861
Citations number
40
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
8
Year of publication
1999
Pages
1845 - 1861
Database
ISI
SICI code
0732-8311(1999)18:8<1845:SABSOM>2.0.ZU;2-Q
Abstract
Novel serine derivative of thymine was prepared and incorporated into oligo nucleotides. These modified oligonucleotides were studied for their binding affinity with complementary DNA/RNA.