Citation
J. Jamison et al., Antiviral activity of magnesium and magnesium/poly r(A-U) combinations against two RNA viruses, NUCLEOS NUC, 18(6-7), 1999, pp. 1221-1222
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311
→ ACNP
Volume
18
Issue
6-7
Year of publication
1999
Pages
1221 - 1222
Database
ISI
SICI code
0732-8311(1999)18:6-7<1221:AAOMAM>2.0.ZU;2-S
Abstract
Magnesium (Mg2+) potentiated the anti-vesicular stomatitis virus (VSV)) act
ivity of poly r(A-U) or poly r(G-C) and the anti-HIV-1 activity of poly r(A
-U) Mg2+ did not affect the anti-VSV activity of poly (rI) . poly (rC), pol
y (dA-dT) . poly (dA-dT) of poly (dG-dC) . poly (dG-dC). Modulation of one
or more nuclear (nuclear) processes of the host cell may be responsible for
the synergistic antiviral activity.