Citation
W. Dabkowski et al., New phosphitylating reagents containing P-F bond and their application in the synthesis of P-fluoro nucleosidyl phosphates, thiophosphates and selenophosphates, NUCLEOS NUC, 18(6-7), 1999, pp. 1247-1248
Citations number
2
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311
→ ACNP
Volume
18
Issue
6-7
Year of publication
1999
Pages
1247 - 1248
Database
ISI
SICI code
0732-8311(1999)18:6-7<1247:NPRCPB>2.0.ZU;2-3
Abstract
An efficient and general synthesis of phosphorofluoridates RO-P(X)(OH)F (X=
O) and their analogues (X=S, Se) based on two new phosphitylating reagents:
2-cyanoethyl-N,N-diisopropylfluorophosphoioamidite F-P(NPr2i)OCH2CH2CN and
tertbutyl-N,N-diisopropylfluorophosphoroamidite F-P(NPr2i)OBut is describe
d.