Synthesis and characterization of oligodeoxynucleotides containing 5 ',8-cyclopurine-2 '-deoxyribonucleosides

Authors
Romieu, A Gasparutto, D Molko, D Cadet, J
Citation
A. Romieu et al., Synthesis and characterization of oligodeoxynucleotides containing 5 ',8-cyclopurine-2 '-deoxyribonucleosides, NUCLEOS NUC, 18(6-7), 1999, pp. 1331-1333
Citations number
6
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
6-7
Year of publication
1999
Pages
1331 - 1333
Database
ISI
SICI code
0732-8311(1999)18:6-7<1331:SACOOC>2.0.ZU;2-S
Abstract
Oligodeoxynucleotides containing the two 5'R and 5'S diastereoisomers of 5' , 8-cyclo-2'-deoxyadenosine (CyclodAdo) and 5',8-cyclo-2'-deoxyguanosine (C yclodGuo) have been synthesized using the phosphoramidite chemistry. The st ructural assignment and a few biochemical features of these modified DNA fr agments are reported.