Interaction of complementary oligonucleotides with the 3 '-end end of yeast tRNA(PHE).

Authors
Petyuk, V Zenkova, M Giege, R Vlassov, V
Citation
V. Petyuk et al., Interaction of complementary oligonucleotides with the 3 '-end end of yeast tRNA(PHE)., NUCLEOS NUC, 18(6-7), 1999, pp. 1459-1461
Citations number
2
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
6-7
Year of publication
1999
Pages
1459 - 1461
Database
ISI
SICI code
0732-8311(1999)18:6-7<1459:IOCOWT>2.0.ZU;2-X
Abstract
Interaction of, yeast tRNA(Phe) With Oligodeoxyribonucleotides (ONs), compl ementary to the nucleotides 62-76 was investigated. Results of gel-mobility shift assay and RNase A probing evidence that the ONs containing the seque nce complementary to the tRNA ACCA end can easily invade the hairpin struct ure under physiological conditions. The limiting step of association proces s is the tRNA unfolding.