Crystal structure of a left-handed Z-DNA hexamer, d(CG)(3), duplex complexed with synthetic polyamine reveals binding of a polyamine in the minor groove

Authors
Tomita, K Ohishi, H Nakanishi, I Hakoshima, T Rich, A
Citation
K. Tomita et al., Crystal structure of a left-handed Z-DNA hexamer, d(CG)(3), duplex complexed with synthetic polyamine reveals binding of a polyamine in the minor groove, NUCLEOS NUC, 18(6-7), 1999, pp. 1567-1569
Citations number
6
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
6-7
Year of publication
1999
Pages
1567 - 1569
Database
ISI
SICI code
0732-8311(1999)18:6-7<1567:CSOALZ>2.0.ZU;2-B
Abstract
As a series of X-ray structural studies of Z-DNA Polyamine complex, the cry stal structure of Z-DNA hexamer, d(CG)(3), duplex complexed with a syntheti c polyamine, N,N'-bis(2-aminoethyl)-1,2-ethanediamine, NH2-(CH2)(2)-NH-(CH2 )(2)-NH(CH2)(2)-NH2 [PA(222)], has been determined.