Crystal and solution structure of the bi-loop motif in cyclic octanucleotides

Authors
Escaja, N Pedroso, E Salisbury, SA Gonzalez, C
Citation
N. Escaja et al., Crystal and solution structure of the bi-loop motif in cyclic octanucleotides, NUCLEOS NUC, 18(6-7), 1999, pp. 1601-1602
Citations number
4
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
6-7
Year of publication
1999
Pages
1601 - 1602
Database
ISI
SICI code
0732-8311(1999)18:6-7<1601:CASSOT>2.0.ZU;2-8
Abstract
The refined NMR structures of the cyclic octamers d<pATTCATTC> 1 and d<pGCT CGCTT> 2 are consistent with the reported crystallographic data of 1 and th e linear heptamer d(GCATGCT), respectively. The NMR study of four new cycli c octamers shows that in all cases a dimeric bi-loop structure is observed in equilibrium with a monomeric form.