Protein and RNA of human telomerase as targets for modified oligonucleotides

Authors
von Janta-Lipinski, M Gaertner, K Lehmann, C Scheer, H Schildt, J Matthes, E
Citation
M. Von Janta-lipinski et al., Protein and RNA of human telomerase as targets for modified oligonucleotides, NUCLEOS NUC, 18(6-7), 1999, pp. 1719-1720
Citations number
7
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
6-7
Year of publication
1999
Pages
1719 - 1720
Database
ISI
SICI code
0732-8311(1999)18:6-7<1719:PAROHT>2.0.ZU;2-3
Abstract
Chimeric oligodeoxynucleotides containing phosphorothioate and N3'-->P5' ph osphoramidate linkages were synthesized. These oligomers show a high inhibi tory activity against human telomerase.