Synthesis of modified thiopurine nucleosides for structural characterization of human thiopurine S-methyltransferase

Authors
Korshunova, GA Krynetski, EY Mtchedlidze, MT Agapkin, DV Evans, WE Krynetskaia, NF
Citation
Ga. Korshunova et al., Synthesis of modified thiopurine nucleosides for structural characterization of human thiopurine S-methyltransferase, NUCLEOS NUC, 18(6-7), 1999, pp. 1747-1748
Citations number
3
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES & NUCLEOTIDES
ISSN journal
07328311 → ACNP
Volume
18
Issue
6-7
Year of publication
1999
Pages
1747 - 1748
Database
ISI
SICI code
0732-8311(1999)18:6-7<1747:SOMTNF>2.0.ZU;2-E
Abstract
Synthesis of a number of photoactive thiopurine-containing nucleosides was described. S-methylation of the synthesized compounds in the course of the reaction catalyzed by recombinant human thiopurine S-methyltransferase was studied by UV-spectroscopy.