Consistency of isochromosome 7q and trisomy 8 in hepatosplenic gamma deltaT-cell lymphoma: Detection by fluorescence in situ hybridization of a splenic touch-preparation from a pediatric patient

Hepatosplenic gamma-delta (gamma delta) T-cell lymphoma is a rare but incre asingly recognized lymphoid malignancy predominantly affecting young adult males. It is not well appreciated in the pediatric population. We report th e third case of this aggressive lymphoma in a child as well as additional s upport for the consistency of the recently discovered cytogenetic abnormali ties, isochromosome 7q and trisomy 8, which in this case were documented us ing fluorescence in situ hybridization (FISH) of a touch-preparation of the spleen.