Cystic adenomatoid malformation of the lung: neonatal management of 21 cases

Currently, congenital cystic adenomatoid malformation of the lung (CCAM) is often diagnosed antenatally by ultrasound, allowing prompt and appropriate medical and surgical management after birth. The authors report 21 cases o f CCAM admitted from 1988 to 1997 to a neonatal intensive care unit and tre ated by high-frequency oscillation (HFO) and early surgery. Six infants dev eloped respiratory distress, of whom 4 required ventilation by HFO. HFO was also the mode of ventilation used in all cases except 1 during the periope rative period. There was no death from respiratory failure. The authors emp hasize the usefulness of antenatal diagnosis, the efficiency of HFO in case s with severe respiratory failure, and well-tolerated early surgery.