We describe 2 patients with acute demyelinating brainstem encephalitis who
were treated with intravenous immunoglobulin (IVIG). Both patients improved
rapidly, concomitant with the course of therapy. To the best of our knowle
dge, these are the first reported cases of brainstem demyelinating lesions
in children treated with IVIG. Our experience suggests that IVIG should be
considered as first-line treatment for similar cases.