In an open study, sildenafil (Viagra) was prescribed for nine women outpati
ents who reported sexual dysfunction induced by antidepressant medication,
primarily selective serotonin reuptake Inhibitors. A 50 mg dose of sildenaf
il was prescribed, and patients were instructed to take it approximately on
e hour before sexual activity. They were told to increase the dose to 100 m
g on the nest occasion if they experienced a partial response or a lack of
response to sildenafil, The nine patients, all of whom had experienced eith
er anorgasmia or delayed orgasm with or without associated disturbances, re
ported significant reversal of sexual dysfunction, usually with the first d
ose of 50 mg of sildenafil.